Drug interactions
Antithrombin alfa + Cefazolin
Severity: Minor
Antithrombin alfa and Cefazolin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cefazolin has no meaningful anticoagulant effect and only a weak theoretical bleeding signal. No clinically significant interaction with antithrombin is established.
What this interaction means in plain words
Antithrombin alfa and Cefazolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism; only a theoretical additive effect on hemostasis.
What to do
No specific action beyond routine monitoring of coagulation during antithrombin therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Cefazolin
- Amikacin + Cefazolin Moderate
- Bcg vaccine live + Cefazolin Moderate
- Cefazolin + Cholera vaccine Moderate
- Cefazolin + Dexamethasone-tobramycin Moderate
- Cefazolin + Gentamicin Moderate
- Cefazolin + Kanamycin Moderate
Frequently asked questions
Can I take Antithrombin alfa with Cefazolin?
MediHelp rates the interaction as minor. Antithrombin alfa and Cefazolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cefazolin has no meaningful anticoagulant effect and only a weak theoretical bleeding signal. No clinically significant interaction with antithrombin is established.
How serious is the interaction between Antithrombin alfa and Cefazolin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action beyond routine monitoring of coagulation during antithrombin therapy.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
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