Drug interactions
Antithymocyte globulin equine + Pneumococcal vaccine 13-valent
Severity: Moderate
Antithymocyte globulin equine and Pneumococcal vaccine 13-valent: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Equine antithymocyte globulin depletes T cells and may markedly reduce the response to pneumococcal conjugate vaccine, though the vaccine is safe.
What this interaction means in plain words
Antithymocyte globulin equine and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Profound T-cell depletion impairs T-cell-dependent antibody production.
What to do
Delay elective vaccination until lymphocyte recovery; vaccinate earlier only if the infection risk is high, then check response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pneumococcal vaccine 13-valent
- Adalimumab + Pneumococcal vaccine 13-valent Moderate
- Alefacept + Pneumococcal vaccine 13-valent Moderate
- Anakinra + Pneumococcal vaccine 13-valent Moderate
- Anti-thymocyte + Pneumococcal vaccine 13-valent Moderate
- Antithymocyte globulin rabbit + Pneumococcal vaccine 13-valent Moderate
- Atidarsagene autotemcel + Pneumococcal vaccine 13-valent Moderate
Frequently asked questions
Can I take Antithymocyte globulin equine with Pneumococcal vaccine 13-valent?
MediHelp rates the interaction as moderate. Antithymocyte globulin equine and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Equine antithymocyte globulin depletes T cells and may markedly reduce the response to pneumococcal conjugate vaccine, though the vaccine is safe.
How serious is the interaction between Antithymocyte globulin equine and Pneumococcal vaccine 13-valent?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Delay elective vaccination until lymphocyte recovery; vaccinate earlier only if the infection risk is high, then check response.
What other medicines interact with Pneumococcal vaccine 13-valent?
MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.
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