Drug interactions
Apixaban + Fish oil triglycerides
Severity: Minor
Apixaban and Fish oil triglycerides: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Omega-3 fatty acids have a mild antiplatelet effect and may slightly prolong bleeding time. With apixaban, bleeding risk may be modestly increased, although clinical events are uncommon.
What this interaction means in plain words
Apixaban and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive pharmacodynamic effect from mild platelet inhibition by omega-3 fatty acids.
What to do
No dose change is generally needed; counsel patients to report bleeding or bruising. Monitor more closely at high omega-3 doses.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Apixaban
- Apixaban + Dabigatran Contraindicated
- Apixaban + Defibrotide Contraindicated
- Apixaban + Edoxaban Contraindicated
- Apixaban + Ketorolac Contraindicated
- Apixaban + Mifepristone Contraindicated
- Abciximab + Apixaban Major
Frequently asked questions
Can I take Apixaban with Fish oil triglycerides?
MediHelp rates the interaction as minor. Apixaban and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Omega-3 fatty acids have a mild antiplatelet effect and may slightly prolong bleeding time. With apixaban, bleeding risk may be modestly increased, although clinical events are uncommon.
How serious is the interaction between Apixaban and Fish oil triglycerides?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is generally needed; counsel patients to report bleeding or bruising. Monitor more closely at high omega-3 doses.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
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