Drug interactions
Arformoterol + Azilsartan-chlorthalidone
Severity: Moderate
Arformoterol and Azilsartan-chlorthalidone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol, a long-acting beta-2 agonist, can lower serum potassium and chlorthalidone adds renal potassium loss. Hypokalemia may increase the risk of arrhythmias, particularly in patients with heart disease.
What this interaction means in plain words
Arformoterol and Azilsartan-chlorthalidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Azilsartan-chlorthalidone belongs to Cardiovascular.
Why it happens
Additive hypokalemia from beta-2 agonist intracellular potassium shift and diuretic-induced renal potassium loss.
What to do
Monitor serum potassium and magnesium, particularly at initiation and in patients with cardiac disease, and correct deficits.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azilsartan-chlorthalidone
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Azilsartan-chlorthalidone?
MediHelp rates the interaction as moderate. Arformoterol and Azilsartan-chlorthalidone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta-2 agonist, can lower serum potassium and chlorthalidone adds renal potassium loss. Hypokalemia may increase the risk of arrhythmias, particularly in patients with heart disease.
How serious is the interaction between Arformoterol and Azilsartan-chlorthalidone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium, particularly at initiation and in patients with cardiac disease, and correct deficits.
What other medicines interact with Azilsartan-chlorthalidone?
MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.
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