Drug interactions
Arformoterol + Azithromycin
Severity: Moderate
Arformoterol and Azithromycin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Long-acting beta-agonists such as arformoterol can prolong the QT interval and lower potassium, and azithromycin adds to QT risk. The combination may raise the likelihood of arrhythmia in susceptible patients.
What this interaction means in plain words
Arformoterol and Azithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Azithromycin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia as a contributing factor.
What to do
Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs. Do not exceed the recommended arformoterol dose.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Azithromycin?
MediHelp rates the interaction as moderate. Arformoterol and Azithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Long-acting beta-agonists such as arformoterol can prolong the QT interval and lower potassium, and azithromycin adds to QT risk. The combination may raise the likelihood of arrhythmia in susceptible patients.
How serious is the interaction between Arformoterol and Azithromycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and serum potassium in patients with cardiac disease or other QT-prolonging drugs. Do not exceed the recommended arformoterol dose.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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