Drug interactions
Arformoterol + Captopril-hydrochlorothiazide
Severity: Moderate
Arformoterol and Captopril-hydrochlorothiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol, a long-acting beta-2 agonist, can lower serum potassium, and hydrochlorothiazide also promotes potassium loss. The combination may cause hypokalemia and ECG changes, particularly in patients with other risk factors.
What this interaction means in plain words
Arformoterol and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Captopril-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Beta-2 agonist driven intracellular potassium shift adds to thiazide renal potassium wasting.
What to do
Monitor serum potassium and replace as needed, especially in patients with cardiac disease or hypoxia.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Arformoterol and Captopril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol, a long-acting beta-2 agonist, can lower serum potassium, and hydrochlorothiazide also promotes potassium loss. The combination may cause hypokalemia and ECG changes, particularly in patients with other risk factors.
How serious is the interaction between Arformoterol and Captopril-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace as needed, especially in patients with cardiac disease or hypoxia.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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