Drug interactions
Arformoterol + Enalapril-hydrochlorothiazide
Severity: Moderate
Arformoterol and Enalapril-hydrochlorothiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both arformoterol and hydrochlorothiazide can lower serum potassium. Combined use may cause hypokalemia and increase the risk of arrhythmia, especially in patients with hypoxia or heart disease.
What this interaction means in plain words
Arformoterol and Enalapril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Enalapril-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Beta-2 agonist-driven potassium shift into cells adds to thiazide-induced renal potassium loss.
What to do
Monitor serum potassium and replace if low, particularly when starting therapy or in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enalapril-hydrochlorothiazide
- Aliskiren + Enalapril-hydrochlorothiazide Contraindicated
- Dofetilide + Enalapril-hydrochlorothiazide Contraindicated
- Enalapril-hydrochlorothiazide + Protein a column Contraindicated
- Enalapril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Amifostine + Enalapril-hydrochlorothiazide Major
- Amiloride + Enalapril-hydrochlorothiazide Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Enalapril-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Arformoterol and Enalapril-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both arformoterol and hydrochlorothiazide can lower serum potassium. Combined use may cause hypokalemia and increase the risk of arrhythmia, especially in patients with hypoxia or heart disease.
How serious is the interaction between Arformoterol and Enalapril-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace if low, particularly when starting therapy or in high-risk patients.
What other medicines interact with Enalapril-hydrochlorothiazide?
MediHelp also lists interactions of Enalapril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Protein a column. The full list is on the Enalapril-hydrochlorothiazide page.
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