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Drug interactions

Arformoterol + Linezolid

Severity: Moderate

Arformoterol and Linezolid: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Long-acting beta-agonists should be given with caution to patients on MAO inhibitors because cardiovascular effects may be potentiated. Linezolid's MAO-inhibiting activity may lead to tachycardia, arrhythmia or blood pressure changes.

What this interaction means in plain words

Arformoterol and Linezolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Arformoterol belongs to Respiratory; Linezolid belongs to Anti Bacterial.

Evidence level: Low

Why it happens

Pharmacodynamic enhancement of adrenergic cardiovascular effects through MAO inhibition by linezolid.

What to do

Monitor heart rate, blood pressure and ECG symptoms during co-therapy. Consider a short-acting alternative or reassess the need for the beta-agonist.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Arformoterol with Linezolid?

MediHelp rates the interaction as moderate. Arformoterol and Linezolid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Long-acting beta-agonists should be given with caution to patients on MAO inhibitors because cardiovascular effects may be potentiated. Linezolid's MAO-inhibiting activity may lead to tachycardia, arrhythmia or blood pressure changes.

How serious is the interaction between Arformoterol and Linezolid?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG symptoms during co-therapy. Consider a short-acting alternative or reassess the need for the beta-agonist.

What other medicines interact with Linezolid?

MediHelp also lists interactions of Linezolid with, for example, Amoxapine, Atomoxetine, Benzphetamine. The full list is on the Linezolid page.

Full monographs, dosing and an interaction checker in the MediHelp app

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