Drug interactions
Arformoterol + Loxapine
Severity: Moderate
Arformoterol and Loxapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Arformoterol is a long-acting beta-2 agonist that can cause tachycardia, hypokalemia and QT prolongation. Loxapine may also prolong the QT interval, so the combination may add to arrhythmia risk.
What this interaction means in plain words
Arformoterol and Loxapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Loxapine belongs to Central Nervous System.
Why it happens
Additive cardiac effects: beta-2 agonist-induced hypokalemia and QT prolongation combined with antipsychotic QT effects.
What to do
Monitor heart rate, potassium and ECG in patients with cardiac disease or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Loxapine
- Alfentanil + Loxapine Major
- Alprazolam + Loxapine Major
- Amisulpride + Loxapine Major
- Amoxapine + Loxapine Major
- Apomorphine + Loxapine Major
- Belladonna and opium + Loxapine Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Loxapine?
MediHelp rates the interaction as moderate. Arformoterol and Loxapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Arformoterol is a long-acting beta-2 agonist that can cause tachycardia, hypokalemia and QT prolongation. Loxapine may also prolong the QT interval, so the combination may add to arrhythmia risk.
How serious is the interaction between Arformoterol and Loxapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, potassium and ECG in patients with cardiac disease or other QT-prolonging drugs.
What other medicines interact with Loxapine?
MediHelp also lists interactions of Loxapine with, for example, Alfentanil, Alprazolam, Amisulpride. The full list is on the Loxapine page.
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