Drug reference
loxapine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic)
Mechanism of action
Dibenzoxazepine antipsychotic; blocks mesolimbic D1 and D2 receptors in the brain; also has anti-serotonin 5HT2 activity
Common side effects
- Constipation
- Hypotension
- Xerostomia
- Akathisia
- Nasal congestion
- Dystonia
- Diminished sweating
Known interactions (4)
- amisulpride + loxapine Major
- bromocriptine + loxapine Major
- cabergoline + loxapine Major
- dopamine + loxapine Moderate
Related conditions
Frequently asked questions
What drug class is loxapine?
loxapine belongs to: Central Nervous System.
How does loxapine work?
Dibenzoxazepine antipsychotic; blocks mesolimbic D1 and D2 receptors in the brain; also has anti-serotonin 5HT2 activity
What are the common side effects of loxapine?
Constipation, Hypotension, Xerostomia, Akathisia, Nasal congestion, Dystonia, Diminished sweating
Which drugs interact with loxapine?
amisulpride, bromocriptine, cabergoline, dopamine
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