Drug interactions
Arformoterol + Primaquine
Severity: Moderate
Arformoterol and Primaquine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Primaquine can prolong the QT interval, and long-acting beta-agonists such as arformoterol can cause tachycardia, hypokalemia and QTc prolongation. Combined use may raise the risk of ventricular arrhythmias in vulnerable patients.
What this interaction means in plain words
Arformoterol and Primaquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Primaquine belongs to Anti Parasitic.
Why it happens
Additive QT prolongation with beta-agonist-related hypokalemia.
What to do
Monitor ECG and potassium in patients with heart disease or other QT risk factors. Correct electrolyte disturbances.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Primaquine
- Pimozide + Primaquine Contraindicated
- Amiodarone + Primaquine Major
- Amisulpride + Primaquine Major
- Anagrelide + Primaquine Major
- Arsenic trioxide + Primaquine Major
- Asenapine + Primaquine Major
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Primaquine?
MediHelp rates the interaction as moderate. Arformoterol and Primaquine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Primaquine can prolong the QT interval, and long-acting beta-agonists such as arformoterol can cause tachycardia, hypokalemia and QTc prolongation. Combined use may raise the risk of ventricular arrhythmias in vulnerable patients.
How serious is the interaction between Arformoterol and Primaquine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and potassium in patients with heart disease or other QT risk factors. Correct electrolyte disturbances.
What other medicines interact with Primaquine?
MediHelp also lists interactions of Primaquine with, for example, Pimozide, Amiodarone, Amisulpride. The full list is on the Primaquine page.
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