Drug reference
primaquine
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Anti Parasitic (Anti Malaria)
Mechanism of action
Disrupts Plasmodium mitochondria
Common side effects
- Vomiting
- Nausea
- Methemoglobinemia
- Hemolytic anemia in G6PD deficiency
- Abdominal pain
Contraindications
- Severe glucose-6-phosphate dehydrogenase (G6PD) deficiency Administration of quinacrine in patients receiving primaquine; administration of primaquine in patients who received quinacrine recently Concurrent administration with other potentially hemolytic drugs or depressants of myeloid elemen…
Known interactions (1)
- dronedarone + primaquine Major
Related conditions
Frequently asked questions
What drug class is primaquine?
primaquine belongs to: Anti Parasitic.
How does primaquine work?
Disrupts Plasmodium mitochondria
What are the common side effects of primaquine?
Vomiting, Nausea, Methemoglobinemia, Hemolytic anemia in G6PD deficiency, Abdominal pain
Which drugs interact with primaquine?
dronedarone
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