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Drug interactions

Arformoterol + Procarbazine

Severity: Moderate

Arformoterol and Procarbazine: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Procarbazine's MAO inhibitory activity can enhance cardiovascular effects of beta-agonists such as arformoterol, with potential for tachycardia, palpitations and blood pressure rises. Labeling for long-acting beta-agonists advises caution with MAO inhibitors.

What this interaction means in plain words

Arformoterol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Arformoterol belongs to Respiratory; Procarbazine belongs to Oncology.

Evidence level: Low

Why it happens

MAO inhibition potentiates the adrenergic cardiovascular effects of the beta-agonist.

What to do

Monitor blood pressure, heart rate and ECG symptoms, and consider an alternative bronchodilator if cardiovascular effects occur.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Arformoterol with Procarbazine?

MediHelp rates the interaction as moderate. Arformoterol and Procarbazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Procarbazine's MAO inhibitory activity can enhance cardiovascular effects of beta-agonists such as arformoterol, with potential for tachycardia, palpitations and blood pressure rises. Labeling for long-acting beta-agonists advises caution with MAO inhibitors.

How serious is the interaction between Arformoterol and Procarbazine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure, heart rate and ECG symptoms, and consider an alternative bronchodilator if cardiovascular effects occur.

What other medicines interact with Procarbazine?

MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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