Drug interactions
Arformoterol + Tranylcypromine
Severity: Moderate
Arformoterol and Tranylcypromine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Labeling advises caution with MAO inhibitors because they may potentiate the vascular effects of long-acting beta-agonists. This can cause tachycardia, QT prolongation and blood pressure changes.
What this interaction means in plain words
Arformoterol and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Arformoterol belongs to Respiratory; Tranylcypromine belongs to Central Nervous System.
Why it happens
MAO inhibition enhances sympathomimetic cardiovascular effects of the beta-agonist.
What to do
Monitor heart rate, blood pressure and ECG if indicated, and reassess the need for the beta-agonist if cardiovascular symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tranylcypromine
- 5-HTP + Tranylcypromine Contraindicated
- Amitriptyline + Tranylcypromine Contraindicated
- Amoxapine + Tranylcypromine Contraindicated
- Atomoxetine + Tranylcypromine Contraindicated
- Benzphetamine + Tranylcypromine Contraindicated
- Brimonidine + Tranylcypromine Contraindicated
Other interactions of Arformoterol
Frequently asked questions
Can I take Arformoterol with Tranylcypromine?
MediHelp rates the interaction as moderate. Arformoterol and Tranylcypromine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Labeling advises caution with MAO inhibitors because they may potentiate the vascular effects of long-acting beta-agonists. This can cause tachycardia, QT prolongation and blood pressure changes.
How serious is the interaction between Arformoterol and Tranylcypromine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and ECG if indicated, and reassess the need for the beta-agonist if cardiovascular symptoms occur.
What other medicines interact with Tranylcypromine?
MediHelp also lists interactions of Tranylcypromine with, for example, 5-HTP, Amitriptyline, Amoxapine. The full list is on the Tranylcypromine page.
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