Drug interactions
Argatroban + Azficel-t
Severity: Moderate
Argatroban and Azficel-t: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azficel-T is given by intradermal injection after a skin biopsy. Anticoagulants such as argatroban may increase bruising and bleeding at the biopsy and injection sites.
What this interaction means in plain words
Argatroban and Azficel-t can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Anticoagulant-induced impairment of hemostasis increases local bleeding and bruising at procedural sites.
What to do
Review the need for anticoagulation around the biopsy and injection procedures, and monitor the sites for bleeding and bruising. Any interruption of anticoagulant therapy should be a physician decision.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Argatroban with Azficel-t?
MediHelp rates the interaction as moderate. Argatroban and Azficel-t can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Azficel-T is given by intradermal injection after a skin biopsy. Anticoagulants such as argatroban may increase bruising and bleeding at the biopsy and injection sites.
How serious is the interaction between Argatroban and Azficel-t?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Review the need for anticoagulation around the biopsy and injection procedures, and monitor the sites for bleeding and bruising. Any interruption of anticoagulant therapy should be a physician decision.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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