Drug interactions
Argatroban + Cinnamon
Severity: Minor
Argatroban and Cinnamon: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Cinnamon contains coumarin, particularly the cassia type, and has been suggested to have mild effects on coagulation. Dietary amounts are unlikely to matter with argatroban, but large supplement doses could add to bleeding risk.
What this interaction means in plain words
Argatroban and Cinnamon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak anticoagulant effect of coumarin constituents; not well established.
What to do
Avoid concentrated cinnamon supplements during argatroban therapy. Monitor aPTT and for bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Argatroban with Cinnamon?
MediHelp rates the interaction as minor. Argatroban and Cinnamon have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cinnamon contains coumarin, particularly the cassia type, and has been suggested to have mild effects on coagulation. Dietary amounts are unlikely to matter with argatroban, but large supplement doses could add to bleeding risk.
How serious is the interaction between Argatroban and Cinnamon?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concentrated cinnamon supplements during argatroban therapy. Monitor aPTT and for bleeding.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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