Drug interactions
Argatroban + Fish oil triglycerides
Severity: Minor
Argatroban and Fish oil triglycerides: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
High-dose omega-3 fatty acids have mild antiplatelet effects and may prolong bleeding time. With argatroban, bleeding risk may be slightly increased.
What this interaction means in plain words
Argatroban and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive effect of omega-3 platelet inhibition with thrombin inhibition.
What to do
Monitor for bleeding and aPTT during argatroban therapy. No dose change is usually needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Argatroban with Fish oil triglycerides?
MediHelp rates the interaction as minor. Argatroban and Fish oil triglycerides have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. High-dose omega-3 fatty acids have mild antiplatelet effects and may prolong bleeding time. With argatroban, bleeding risk may be slightly increased.
How serious is the interaction between Argatroban and Fish oil triglycerides?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and aPTT during argatroban therapy. No dose change is usually needed.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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