Drug interactions
Argatroban + Forskolin
Severity: Minor
Argatroban and Forskolin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Forskolin raises intracellular cAMP and can inhibit platelet aggregation. Additive bleeding risk with argatroban is theoretical.
What this interaction means in plain words
Argatroban and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Adenylate cyclase activation reduces platelet activation, adding to thrombin inhibition.
What to do
Discourage forskolin supplements during argatroban therapy. Monitor aPTT and for bleeding.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Argatroban with Forskolin?
MediHelp rates the interaction as minor. Argatroban and Forskolin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Forskolin raises intracellular cAMP and can inhibit platelet aggregation. Additive bleeding risk with argatroban is theoretical.
How serious is the interaction between Argatroban and Forskolin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Discourage forskolin supplements during argatroban therapy. Monitor aPTT and for bleeding.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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