Drug interactions
Argatroban + Nettle
Severity: Minor
Argatroban and Nettle: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nettle contains vitamin K and may reduce the effect of vitamin K antagonists, but it has no established effect on direct thrombin inhibitors. Interaction with argatroban is unclear and likely negligible.
What this interaction means in plain words
Argatroban and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
No established mechanism for argatroban; the vitamin K content is relevant mainly to warfarin.
What to do
No specific action is needed beyond routine aPTT monitoring during argatroban.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Argatroban
- Argatroban + Defibrotide Contraindicated
- Argatroban + Ketorolac Contraindicated
- Argatroban + Mifepristone Contraindicated
- Abciximab + Argatroban Major
- Acalabrutinib + Argatroban Major
- Acetylsalicylic acid + Argatroban Major
Frequently asked questions
Can I take Argatroban with Nettle?
MediHelp rates the interaction as minor. Argatroban and Nettle have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nettle contains vitamin K and may reduce the effect of vitamin K antagonists, but it has no established effect on direct thrombin inhibitors. Interaction with argatroban is unclear and likely negligible.
How serious is the interaction between Argatroban and Nettle?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond routine aPTT monitoring during argatroban.
What other medicines interact with Argatroban?
MediHelp also lists interactions of Argatroban with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Argatroban page.
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