Drug interactions
Aripiprazole + Buprenorphine subdermal implant
Severity: Minor
Aripiprazole and Buprenorphine subdermal implant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Buprenorphine has a small QT-prolonging effect, and the implant gives low steady exposure. With aripiprazole, the added QT risk is modest, but sedation can also be additive.
What this interaction means in plain words
Aripiprazole and Buprenorphine subdermal implant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive QT prolongation and CNS depression.
What to do
No routine change is needed, but obtain an ECG if other QT risk factors exist and monitor for sedation.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Aripiprazole and Buprenorphine subdermal implant, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Buprenorphine subdermal implant?
MediHelp rates the interaction as minor. Aripiprazole and Buprenorphine subdermal implant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Buprenorphine has a small QT-prolonging effect, and the implant gives low steady exposure. With aripiprazole, the added QT risk is modest, but sedation can also be additive.
How serious is the interaction between Aripiprazole and Buprenorphine subdermal implant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed, but obtain an ECG if other QT risk factors exist and monitor for sedation.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
