Drug reference
aripiprazole
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Central Nervous System (Anti Psychotic (atypical))
Mechanism of action
Atypical antipsychotic; partial agonist at dopamine D2 and serotonin type 1 (5-HT1A) receptors; antagonist at serotonin type 2 (5-HT2A) receptor; also has alpha-blocking activity
Common side effects
- Insomnia
- Agitation
- Headache
- Anxiety
- Akathisia
- Weight gain
Known interactions (13)
- aripiprazole + pimozide Contraindicated
- aripiprazole + thioridazine Contraindicated
- amisulpride + aripiprazole Major
- aripiprazole + cisapride Major
- aripiprazole + dronedarone Major
- aripiprazole + quinidine Major
- aripiprazole + cabergoline Moderate
- aripiprazole + dopamine Moderate
- aripiprazole + fluconazole Moderate
- aripiprazole + methyldopa Moderate
- aripiprazole + posaconazole Moderate
- aripiprazole + pramipexole Moderate
- aripiprazole + ropinirole Moderate
Related conditions
Frequently asked questions
What drug class is aripiprazole?
aripiprazole belongs to: Central Nervous System.
How does aripiprazole work?
Atypical antipsychotic; partial agonist at dopamine D2 and serotonin type 1 (5-HT1A) receptors; antagonist at serotonin type 2 (5-HT2A) receptor; also has alpha-blocking activity
What are the common side effects of aripiprazole?
Insomnia, Agitation, Headache, Anxiety, Akathisia, Weight gain
Which drugs interact with aripiprazole?
pimozide, thioridazine, amisulpride, cisapride, dronedarone, quinidine, cabergoline, dopamine, fluconazole, methyldopa, posaconazole, pramipexole, ropinirole
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