Drug interactions
Aripiprazole + Chasteberry
Severity: Minor
Aripiprazole and Chasteberry: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Chasteberry is thought to have dopaminergic activity and could theoretically blunt the dopamine antagonist or partial agonist effects of aripiprazole. No clinically meaningful reductions in antipsychotic efficacy have been well documented.
What this interaction means in plain words
Aripiprazole and Chasteberry have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical pharmacodynamic opposition at dopamine D2 receptors.
What to do
No routine change is needed. Monitor psychiatric symptoms if chasteberry is started or stopped in a patient on aripiprazole.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Chasteberry?
MediHelp rates the interaction as minor. Aripiprazole and Chasteberry have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Chasteberry is thought to have dopaminergic activity and could theoretically blunt the dopamine antagonist or partial agonist effects of aripiprazole. No clinically meaningful reductions in antipsychotic efficacy have been well documented.
How serious is the interaction between Aripiprazole and Chasteberry?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor psychiatric symptoms if chasteberry is started or stopped in a patient on aripiprazole.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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