Drug interactions
Aripiprazole + Dichlorphenamide
Severity: Minor
Aripiprazole and Dichlorphenamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide can cause hypokalemia and metabolic acidosis. Low potassium raises the risk of arrhythmia, which matters when combined with drugs that have any QT liability, although aripiprazole's effect is small.
What this interaction means in plain words
Aripiprazole and Dichlorphenamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Dichlorphenamide belongs to Miscellaneous.
Why it happens
Carbonic anhydrase inhibition causes renal potassium loss, which may increase arrhythmia susceptibility.
What to do
Monitor serum potassium and bicarbonate periodically and replace potassium as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Aripiprazole with Dichlorphenamide?
MediHelp rates the interaction as minor. Aripiprazole and Dichlorphenamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dichlorphenamide can cause hypokalemia and metabolic acidosis. Low potassium raises the risk of arrhythmia, which matters when combined with drugs that have any QT liability, although aripiprazole's effect is small.
How serious is the interaction between Aripiprazole and Dichlorphenamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and bicarbonate periodically and replace potassium as needed.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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