Drug interactions
Aripiprazole + Ethanol
Severity: Moderate
Aripiprazole and Ethanol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Alcohol can add to the sedative and psychomotor effects of aripiprazole, impairing alertness, coordination, and judgement. It may also worsen orthostatic hypotension and undermine psychiatric stability.
What this interaction means in plain words
Aripiprazole and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depression.
What to do
Advise patients to avoid or minimize alcohol and not to drive or use machinery after drinking.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Ethanol?
MediHelp rates the interaction as moderate. Aripiprazole and Ethanol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Alcohol can add to the sedative and psychomotor effects of aripiprazole, impairing alertness, coordination, and judgement. It may also worsen orthostatic hypotension and undermine psychiatric stability.
How serious is the interaction between Aripiprazole and Ethanol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid or minimize alcohol and not to drive or use machinery after drinking.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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