Drug interactions
Aripiprazole + Exenatide
Severity: Minor
Aripiprazole and Exenatide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atypical antipsychotics can impair glucose control, though aripiprazole has a relatively low metabolic risk. This may partly offset the glucose-lowering effect of exenatide.
What this interaction means in plain words
Aripiprazole and Exenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Aripiprazole belongs to Central Nervous System; Exenatide belongs to Endocrine.
Why it happens
Pharmacodynamic opposition: antipsychotic-related insulin resistance may counter exenatide's effect.
What to do
Monitor glucose and HbA1c periodically after starting aripiprazole.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Exenatide
- Chlorpropamide + Exenatide Major
- Asenapine + Exenatide Moderate
- Betamethasone + Exenatide Moderate
- Chlorothiazide + Exenatide Moderate
- Clozapine + Exenatide Moderate
- Cortisone + Exenatide Moderate
Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Exenatide?
MediHelp rates the interaction as minor. Aripiprazole and Exenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atypical antipsychotics can impair glucose control, though aripiprazole has a relatively low metabolic risk. This may partly offset the glucose-lowering effect of exenatide.
How serious is the interaction between Aripiprazole and Exenatide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose and HbA1c periodically after starting aripiprazole.
What other medicines interact with Exenatide?
MediHelp also lists interactions of Exenatide with, for example, Chlorpropamide, Asenapine, Betamethasone. The full list is on the Exenatide page.
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