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Drug interactions

Aripiprazole + Motherwort

Severity: Minor

Aripiprazole and Motherwort: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Motherwort has mild sedative properties and may add to the drowsiness caused by aripiprazole. Evidence is limited to traditional use and theory.

What this interaction means in plain words

Aripiprazole and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive CNS depressant effects; mechanism is not well characterized.

What to do

Advise patients to watch for excess drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation occurs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Aripiprazole with Motherwort?

MediHelp rates the interaction as minor. Aripiprazole and Motherwort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Motherwort has mild sedative properties and may add to the drowsiness caused by aripiprazole. Evidence is limited to traditional use and theory.

How serious is the interaction between Aripiprazole and Motherwort?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to watch for excess drowsiness and avoid driving if affected. Consider stopping the herbal product if sedation occurs.

What other medicines interact with Aripiprazole?

MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.

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