Drug interactions
Aripiprazole + Olopatadine intranasal
Severity: Minor
Aripiprazole and Olopatadine intranasal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Intranasal olopatadine can cause somnolence, and aripiprazole can also cause sedation. Together they may increase drowsiness and impair psychomotor performance.
What this interaction means in plain words
Aripiprazole and Olopatadine intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depressant effects from H1 antihistamine and antipsychotic activity.
What to do
Advise patients to avoid driving or hazardous tasks until they know how the combination affects them. Avoid additional sedatives such as alcohol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Olopatadine intranasal?
MediHelp rates the interaction as minor. Aripiprazole and Olopatadine intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Intranasal olopatadine can cause somnolence, and aripiprazole can also cause sedation. Together they may increase drowsiness and impair psychomotor performance.
How serious is the interaction between Aripiprazole and Olopatadine intranasal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid driving or hazardous tasks until they know how the combination affects them. Avoid additional sedatives such as alcohol.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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