Drug interactions
Aripiprazole + Pholcodine
Severity: Minor
Aripiprazole and Pholcodine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pholcodine is an opioid antitussive with sedative potential, which may add to the drowsiness caused by aripiprazole. At cough-suppressant doses the effect is generally small.
What this interaction means in plain words
Aripiprazole and Pholcodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive CNS depression.
What to do
Advise patients about possible drowsiness and caution when driving. Avoid combining with other sedatives or alcohol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Pholcodine?
MediHelp rates the interaction as minor. Aripiprazole and Pholcodine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pholcodine is an opioid antitussive with sedative potential, which may add to the drowsiness caused by aripiprazole. At cough-suppressant doses the effect is generally small.
How serious is the interaction between Aripiprazole and Pholcodine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients about possible drowsiness and caution when driving. Avoid combining with other sedatives or alcohol.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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