Drug interactions
Aripiprazole + Scullcap
Severity: Minor
Aripiprazole and Scullcap: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Scullcap is used traditionally as a sedative herb, and it may add to the drowsiness caused by aripiprazole. Evidence is limited and product quality varies.
What this interaction means in plain words
Aripiprazole and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive CNS depression; mechanism of the herb is not well established.
What to do
Advise patients to disclose herbal use and watch for excess drowsiness. Avoid combining if sedation affects daily function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Aripiprazole
- Aripiprazole + Pimozide Contraindicated
- Aripiprazole + Thioridazine Contraindicated
- Amisulpride + Aripiprazole Major
- Aripiprazole + Arsenic trioxide Major
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Major
- Aripiprazole + Carbamazepine Major
Frequently asked questions
Can I take Aripiprazole with Scullcap?
MediHelp rates the interaction as minor. Aripiprazole and Scullcap have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Scullcap is used traditionally as a sedative herb, and it may add to the drowsiness caused by aripiprazole. Evidence is limited and product quality varies.
How serious is the interaction between Aripiprazole and Scullcap?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to disclose herbal use and watch for excess drowsiness. Avoid combining if sedation affects daily function.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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