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Drug interactions

Aripiprazole + Vilanterol / fluticasone furoate inhaled

Severity: Minor

Aripiprazole and Vilanterol / fluticasone furoate inhaled: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Inhaled vilanterol is a beta-agonist with low systemic exposure that can occasionally cause QT prolongation or hypokalemia. With aripiprazole the added risk is small but may matter in susceptible patients.

What this interaction means in plain words

Aripiprazole and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Possible additive QT effect and beta-agonist-induced hypokalemia.

What to do

No routine change is needed; consider ECG and potassium monitoring in patients with cardiac disease or other QT-prolonging drugs.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Aripiprazole with Vilanterol / fluticasone furoate inhaled?

MediHelp rates the interaction as minor. Aripiprazole and Vilanterol / fluticasone furoate inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Inhaled vilanterol is a beta-agonist with low systemic exposure that can occasionally cause QT prolongation or hypokalemia. With aripiprazole the added risk is small but may matter in susceptible patients.

How serious is the interaction between Aripiprazole and Vilanterol / fluticasone furoate inhaled?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; consider ECG and potassium monitoring in patients with cardiac disease or other QT-prolonging drugs.

What other medicines interact with Aripiprazole?

MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.

Full monographs, dosing and an interaction checker in the MediHelp app

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