Drug interactions
Artemether + Fluticasone-vilanterol
Severity: Moderate
Artemether and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Artemether, usually given with lumefantrine, can prolong the QT interval. Vilanterol, a beta2-agonist, may add to this effect and lower potassium, slightly raising arrhythmia risk.
What this interaction means in plain words
Artemether and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive effects on cardiac repolarization, with beta2-agonist-related hypokalemia.
What to do
Check potassium and magnesium and obtain an ECG if other QT risk factors exist. Counsel the patient to report palpitations or fainting.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Frequently asked questions
Can I take Artemether with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Artemether and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Artemether, usually given with lumefantrine, can prolong the QT interval. Vilanterol, a beta2-agonist, may add to this effect and lower potassium, slightly raising arrhythmia risk.
How serious is the interaction between Artemether and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and obtain an ECG if other QT risk factors exist. Counsel the patient to report palpitations or fainting.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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