Drug interactions
Artemether + Vardenafil
Severity: Moderate
Artemether and Vardenafil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can prolong the QT interval, so combined use may increase the risk of ventricular arrhythmia. The risk is higher with electrolyte disturbance or other QT-active drugs.
What this interaction means in plain words
Artemether and Vardenafil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive QT interval prolongation.
What to do
Check an ECG and correct potassium and magnesium before use. Avoid in patients with congenital long QT or other QT-prolonging drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Vardenafil
- Amyl nitrite + Vardenafil Contraindicated
- Glyceryl trinitrate pr + Vardenafil Contraindicated
- Isosorbide dinitrate + Vardenafil Contraindicated
- Isosorbide mononitrate + Vardenafil Contraindicated
- Nicorandil + Vardenafil Contraindicated
- Nitroglycerin po + Vardenafil Contraindicated
Frequently asked questions
Can I take Artemether with Vardenafil?
MediHelp rates the interaction as moderate. Artemether and Vardenafil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents can prolong the QT interval, so combined use may increase the risk of ventricular arrhythmia. The risk is higher with electrolyte disturbance or other QT-active drugs.
How serious is the interaction between Artemether and Vardenafil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check an ECG and correct potassium and magnesium before use. Avoid in patients with congenital long QT or other QT-prolonging drugs.
What other medicines interact with Vardenafil?
MediHelp also lists interactions of Vardenafil with, for example, Amyl nitrite, Glyceryl trinitrate pr, Isosorbide dinitrate. The full list is on the Vardenafil page.
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