Drug interactions
Carvedilol + Formoterol-mometasone
Severity: Major
Carvedilol and Formoterol-mometasone: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Carvedilol is a nonselective beta-blocker that can antagonize formoterol and provoke bronchospasm in patients with asthma or COPD. This may reduce rescue and maintenance bronchodilator efficacy and worsen airway control.
What this interaction means in plain words
Carvedilol and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Carvedilol belongs to Cardiovascular; Formoterol-mometasone belongs to Respiratory.
Why it happens
Competitive pharmacodynamic antagonism at beta-1 and beta-2 adrenergic receptors.
What to do
Avoid carvedilol in patients with asthma and use a cardioselective beta-blocker if one is required. In COPD, monitor respiratory status closely.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Formoterol-mometasone
Other interactions of Carvedilol
Frequently asked questions
Can I take Carvedilol with Formoterol-mometasone?
MediHelp rates the interaction as major. Carvedilol and Formoterol-mometasone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Carvedilol is a nonselective beta-blocker that can antagonize formoterol and provoke bronchospasm in patients with asthma or COPD. This may reduce rescue and maintenance bronchodilator efficacy and worsen airway control.
How serious is the interaction between Carvedilol and Formoterol-mometasone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid carvedilol in patients with asthma and use a cardioselective beta-blocker if one is required. In COPD, monitor respiratory status closely.
What other medicines interact with Formoterol-mometasone?
MediHelp also lists interactions of Formoterol-mometasone with, for example, Amiodarone, Amisulpride, Amoxapine. The full list is on the Formoterol-mometasone page.
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