Drug interactions
astemizole + clarithromycin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Overview
Torsades risk; contraindicated (historical).
Mechanism of action
CYP3A4 inhibition.
Clinical management
Avoid (drug withdrawn in many markets).
Drug reference
References
Frequently asked questions
Can I take astemizole with clarithromycin?
The interaction is rated: Contraindicated. Torsades risk; contraindicated (historical).
How serious is the interaction between astemizole and clarithromycin?
The interaction is rated: Contraindicated. Evidence level: High.
How is the interaction between astemizole and clarithromycin managed?
Avoid (drug withdrawn in many markets).
Why do astemizole and clarithromycin interact?
CYP3A4 inhibition.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.