Drug interactions
Atazanavir + Exenatide
Severity: Minor
Atazanavir and Exenatide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Protease inhibitors can induce insulin resistance and hyperglycemia, although atazanavir has a relatively favorable metabolic profile. This may partly offset the glucose-lowering effect of exenatide.
What this interaction means in plain words
Atazanavir and Exenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atazanavir belongs to Anti Virals; Exenatide belongs to Endocrine.
Why it happens
Protease inhibitor effects on insulin sensitivity oppose the glucose-lowering action of exenatide (pharmacodynamic antagonism).
What to do
Monitor blood glucose when starting or stopping atazanavir and adjust antidiabetic therapy as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Exenatide
- Chlorpropamide + Exenatide Major
- Asenapine + Exenatide Moderate
- Betamethasone + Exenatide Moderate
- Chlorothiazide + Exenatide Moderate
- Clozapine + Exenatide Moderate
- Cortisone + Exenatide Moderate
Other interactions of Atazanavir
- Alfuzosin + Atazanavir Contraindicated
- Atazanavir + Avanafil Contraindicated
- Atazanavir + Dronedarone Contraindicated
- Atazanavir + Eletriptan Contraindicated
- Atazanavir + Eplerenone Contraindicated
- Atazanavir + Ergotamine Contraindicated
Frequently asked questions
Can I take Atazanavir with Exenatide?
MediHelp rates the interaction as minor. Atazanavir and Exenatide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Protease inhibitors can induce insulin resistance and hyperglycemia, although atazanavir has a relatively favorable metabolic profile. This may partly offset the glucose-lowering effect of exenatide.
How serious is the interaction between Atazanavir and Exenatide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when starting or stopping atazanavir and adjust antidiabetic therapy as needed.
What other medicines interact with Exenatide?
MediHelp also lists interactions of Exenatide with, for example, Chlorpropamide, Asenapine, Betamethasone. The full list is on the Exenatide page.
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