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Drug interactions

Atazanavir + Insulin detemir

Severity: Minor

Atazanavir and Insulin detemir: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Protease inhibitors may cause insulin resistance and hyperglycemia in some patients, reducing insulin effect. Atazanavir has less metabolic impact than some other agents in the class.

What this interaction means in plain words

Atazanavir and Insulin detemir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Atazanavir belongs to Anti Virals; Insulin detemir belongs to Endocrine.

Evidence level: Low

Why it happens

Protease inhibitors can impair peripheral glucose uptake and insulin sensitivity, though atazanavir has relatively limited effect.

What to do

Monitor blood glucose after starting atazanavir. Adjust insulin detemir dose if control worsens.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Atazanavir with Insulin detemir?

MediHelp rates the interaction as minor. Atazanavir and Insulin detemir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Protease inhibitors may cause insulin resistance and hyperglycemia in some patients, reducing insulin effect. Atazanavir has less metabolic impact than some other agents in the class.

How serious is the interaction between Atazanavir and Insulin detemir?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting atazanavir. Adjust insulin detemir dose if control worsens.

What other medicines interact with Insulin detemir?

MediHelp also lists interactions of Insulin detemir with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin detemir page.

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