Drug interactions
Atenolol + Captopril-hydrochlorothiazide
Severity: Minor
Atenolol and Captopril-hydrochlorothiazide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atenolol and the captopril-hydrochlorothiazide combination are commonly used together and have additive blood pressure lowering. Beta-blockers may blunt hypoglycemia awareness and thiazides may modestly raise glucose, but no important potassium interaction is expected.
What this interaction means in plain words
Atenolol and Captopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol belongs to Cardiovascular; Captopril-hydrochlorothiazide belongs to Cardiovascular.
Why it happens
Additive antihypertensive effect through different pathways.
What to do
Monitor blood pressure and heart rate when combining. Adjust doses if hypotension or bradycardia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Captopril-hydrochlorothiazide
- Aliskiren + Captopril-hydrochlorothiazide Contraindicated
- Captopril-hydrochlorothiazide + Dofetilide Contraindicated
- Captopril-hydrochlorothiazide + Sacubitril / valsartan Contraindicated
- Aceclofenac + Captopril-hydrochlorothiazide Major
- Aldesleukin + Captopril-hydrochlorothiazide Major
- Amifostine + Captopril-hydrochlorothiazide Major
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Captopril-hydrochlorothiazide?
MediHelp rates the interaction as minor. Atenolol and Captopril-hydrochlorothiazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atenolol and the captopril-hydrochlorothiazide combination are commonly used together and have additive blood pressure lowering. Beta-blockers may blunt hypoglycemia awareness and thiazides may modestly raise glucose, but no important potassium interaction is expected.
How serious is the interaction between Atenolol and Captopril-hydrochlorothiazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when combining. Adjust doses if hypotension or bradycardia occurs.
What other medicines interact with Captopril-hydrochlorothiazide?
MediHelp also lists interactions of Captopril-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sacubitril / valsartan. The full list is on the Captopril-hydrochlorothiazide page.
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