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Drug interactions

Atenolol + Felodipine

Severity: Minor

Atenolol and Felodipine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Felodipine is a dihydropyridine vasodilator, and combining it with atenolol is a common, well-tolerated antihypertensive regimen. Blood pressure lowering is additive, and atenolol can blunt the reflex tachycardia from felodipine. Occasional hypotension or peripheral edema may occur.

What this interaction means in plain words

Atenolol and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Atenolol belongs to Cardiovascular; Felodipine belongs to Cardiovascular.

Evidence level: High

Why it happens

Complementary hypotensive effects from calcium channel blockade and beta blockade.

What to do

Monitor blood pressure and heart rate when starting or adjusting doses; no routine dose change is needed.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Atenolol with Felodipine?

MediHelp rates the interaction as minor. Atenolol and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Felodipine is a dihydropyridine vasodilator, and combining it with atenolol is a common, well-tolerated antihypertensive regimen. Blood pressure lowering is additive, and atenolol can blunt the reflex tachycardia from felodipine. Occasional hypotension or peripheral edema may occur.

How serious is the interaction between Atenolol and Felodipine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses; no routine dose change is needed.

What other medicines interact with Atenolol?

MediHelp also lists interactions of Atenolol with, for example, Amifostine, Amiodarone, Atenolol-chlorthalidone. The full list is on the Atenolol page.

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