Drug interactions
Atenolol + Ipratropium-salbutamol
Severity: Moderate
Atenolol and Ipratropium-salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atenolol is a beta-1 selective blocker that can reduce the bronchodilating effect of salbutamol and in higher doses may provoke bronchospasm in reactive airway disease. Selectivity is relative and lost at higher doses.
What this interaction means in plain words
Atenolol and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Ipratropium-salbutamol belongs to Respiratory.
Why it happens
Pharmacodynamic antagonism of beta-adrenergic receptors.
What to do
Use the lowest atenolol dose in patients with asthma or COPD, or choose a non-beta-blocker where possible. Monitor respiratory symptoms and response to salbutamol.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atenolol and Ipratropium-salbutamol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Ipratropium-salbutamol
Other interactions of Atenolol
- Amifostine + Atenolol Major
- Amiodarone + Atenolol Major
- Atenolol + Atenolol-chlorthalidone Major
- Atenolol + Betaxolol Major
- Atenolol + Bisoprolol Major
- Atenolol + Carvedilol Major
Frequently asked questions
Can I take Atenolol with Ipratropium-salbutamol?
MediHelp rates the interaction as moderate. Atenolol and Ipratropium-salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atenolol is a beta-1 selective blocker that can reduce the bronchodilating effect of salbutamol and in higher doses may provoke bronchospasm in reactive airway disease. Selectivity is relative and lost at higher doses.
How serious is the interaction between Atenolol and Ipratropium-salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest atenolol dose in patients with asthma or COPD, or choose a non-beta-blocker where possible. Monitor respiratory symptoms and response to salbutamol.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
