Drug interactions
Atenolol-chlorthalidone + Corticotropin
Severity: Moderate
Atenolol-chlorthalidone and Corticotropin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Corticotropin stimulates corticosteroid release, which promotes potassium excretion. Combined with chlorthalidone this can lead to additive hypokalemia and fluid retention.
What this interaction means in plain words
Atenolol-chlorthalidone and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Corticotropin belongs to Endocrine.
Why it happens
Additive renal potassium wasting from mineralocorticoid effects plus thiazide diuresis.
What to do
Monitor serum potassium and replace potassium as needed. Check blood pressure and fluid status during therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Atenolol-chlorthalidone
Other interactions of Corticotropin
- Alogliptin-metformin + Corticotropin Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Corticotropin Moderate
- Amlodipine-olmesartan-hydrochlorothiazide + Corticotropin Moderate
- Amphotericin b + Corticotropin Moderate
- Atracurium + Corticotropin Moderate
- Azilsartan-chlorthalidone + Corticotropin Moderate
Frequently asked questions
Can I take Atenolol-chlorthalidone with Corticotropin?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Corticotropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Corticotropin stimulates corticosteroid release, which promotes potassium excretion. Combined with chlorthalidone this can lead to additive hypokalemia and fluid retention.
How serious is the interaction between Atenolol-chlorthalidone and Corticotropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and replace potassium as needed. Check blood pressure and fluid status during therapy.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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