Drug interactions
Atenolol-chlorthalidone + Felodipine
Severity: Minor
Atenolol-chlorthalidone and Felodipine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Felodipine is a vasodilating dihydropyridine calcium channel blocker, so combined with atenolol and chlorthalidone it increases blood pressure reduction. This combination is commonly used therapeutically, but hypotension and peripheral edema can occur.
What this interaction means in plain words
Atenolol-chlorthalidone and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atenolol-chlorthalidone belongs to Cardiovascular; Felodipine belongs to Cardiovascular.
Why it happens
Additive antihypertensive effects through vasodilation, beta-blockade and diuresis.
What to do
Monitor blood pressure and heart rate when starting or adjusting doses; adjust either drug if symptomatic hypotension occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atenolol-chlorthalidone
Other interactions of Felodipine
- Felodipine + Itraconazole Contraindicated
- Aldesleukin + Felodipine Major
- Amifostine + Felodipine Major
- Apalutamide + Felodipine Major
- Atazanavir + Felodipine Major
- Carbamazepine + Felodipine Major
Frequently asked questions
Can I take Atenolol-chlorthalidone with Felodipine?
MediHelp rates the interaction as minor. Atenolol-chlorthalidone and Felodipine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Felodipine is a vasodilating dihydropyridine calcium channel blocker, so combined with atenolol and chlorthalidone it increases blood pressure reduction. This combination is commonly used therapeutically, but hypotension and peripheral edema can occur.
How serious is the interaction between Atenolol-chlorthalidone and Felodipine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate when starting or adjusting doses; adjust either drug if symptomatic hypotension occurs.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
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