Drug interactions
Atenolol-chlorthalidone + Nimodipine
Severity: Moderate
Atenolol-chlorthalidone and Nimodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nimodipine can cause marked hypotension, and the effect adds to that of atenolol and chlorthalidone. This is especially relevant in patients with subarachnoid hemorrhage where cerebral perfusion pressure must be maintained.
What this interaction means in plain words
Atenolol-chlorthalidone and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Nimodipine belongs to Cardiovascular.
Why it happens
Additive blood pressure lowering from calcium channel blockade, beta-blockade and diuretic-induced volume depletion.
What to do
Monitor blood pressure frequently, particularly at nimodipine initiation. Consider holding or reducing other antihypertensives if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Atenolol-chlorthalidone and Nimodipine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Atenolol-chlorthalidone
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Atenolol-chlorthalidone with Nimodipine?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Nimodipine can cause marked hypotension, and the effect adds to that of atenolol and chlorthalidone. This is especially relevant in patients with subarachnoid hemorrhage where cerebral perfusion pressure must be maintained.
How serious is the interaction between Atenolol-chlorthalidone and Nimodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure frequently, particularly at nimodipine initiation. Consider holding or reducing other antihypertensives if hypotension develops.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
