Drug interactions
Atomoxetine + Azithromycin
Severity: Moderate
Atomoxetine and Azithromycin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval, and atomoxetine also raises heart rate and blood pressure. Combined use may add to arrhythmic risk in susceptible patients.
What this interaction means in plain words
Atomoxetine and Azithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Azithromycin belongs to Anti Bacterial.
Why it happens
Possible additive QT prolongation.
What to do
Monitor ECG and electrolytes in patients with cardiac risk factors. Consider an alternative antibiotic in those with long QT or structural heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Azithromycin
- Azithromycin + Cisapride Contraindicated
- Azithromycin + Domperidone Contraindicated
- Azithromycin + Dronedarone Contraindicated
- Azithromycin + Pimozide Contraindicated
- Azithromycin + Piperaquine Contraindicated
- Azithromycin + Thioridazine Contraindicated
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Azithromycin?
MediHelp rates the interaction as moderate. Atomoxetine and Azithromycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval, and atomoxetine also raises heart rate and blood pressure. Combined use may add to arrhythmic risk in susceptible patients.
How serious is the interaction between Atomoxetine and Azithromycin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG and electrolytes in patients with cardiac risk factors. Consider an alternative antibiotic in those with long QT or structural heart disease.
What other medicines interact with Azithromycin?
MediHelp also lists interactions of Azithromycin with, for example, Cisapride, Domperidone, Dronedarone. The full list is on the Azithromycin page.
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