Drug interactions
Atomoxetine + Ciprofloxacin
Severity: Moderate
Atomoxetine and Ciprofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can prolong the QT interval, and atomoxetine may raise heart rate and blood pressure. Combined use may increase arrhythmia risk, mainly in patients with other cardiac or electrolyte risk factors.
What this interaction means in plain words
Atomoxetine and Ciprofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Ciprofloxacin belongs to Anti Bacterial.
Why it happens
Additive effects on cardiac repolarization (QT prolongation).
What to do
Screen for congenital long QT, bradycardia and electrolyte abnormalities before combining. Monitor ECG and symptoms such as palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicated
- Ciprofloxacin + Fezolinetant Contraindicated
- Ciprofloxacin + Thioridazine Contraindicated
- Ciprofloxacin + Tizanidine Contraindicated
- Ciprofloxacin + Vandetanib Contraindicated
- Alosetron + Ciprofloxacin Major
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Ciprofloxacin?
MediHelp rates the interaction as moderate. Atomoxetine and Ciprofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can prolong the QT interval, and atomoxetine may raise heart rate and blood pressure. Combined use may increase arrhythmia risk, mainly in patients with other cardiac or electrolyte risk factors.
How serious is the interaction between Atomoxetine and Ciprofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Screen for congenital long QT, bradycardia and electrolyte abnormalities before combining. Monitor ECG and symptoms such as palpitations or syncope.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
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