Drug interactions
Atomoxetine + Fluticasone-vilanterol
Severity: Moderate
Atomoxetine and Fluticasone-vilanterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atomoxetine raises heart rate and blood pressure and has been linked to QT prolongation in overdose, and vilanterol adds beta2-mediated cardiac stimulation. The combination may increase tachycardia and palpitations.
What this interaction means in plain words
Atomoxetine and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Fluticasone-vilanterol belongs to Respiratory.
Why it happens
Additive sympathomimetic cardiovascular effects and possible QT effects.
What to do
Monitor heart rate, blood pressure and symptoms of arrhythmia, especially with underlying heart disease.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fluticasone-vilanterol
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Fluticasone-vilanterol?
MediHelp rates the interaction as moderate. Atomoxetine and Fluticasone-vilanterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atomoxetine raises heart rate and blood pressure and has been linked to QT prolongation in overdose, and vilanterol adds beta2-mediated cardiac stimulation. The combination may increase tachycardia and palpitations.
How serious is the interaction between Atomoxetine and Fluticasone-vilanterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and symptoms of arrhythmia, especially with underlying heart disease.
What other medicines interact with Fluticasone-vilanterol?
MediHelp also lists interactions of Fluticasone-vilanterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Fluticasone-vilanterol page.
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