Drug interactions
Atomoxetine + Levofloxacin
Severity: Moderate
Atomoxetine and Levofloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs have been linked to QTc prolongation, so use together may increase arrhythmia risk. The concern is greater with heart disease, bradycardia, or electrolyte abnormalities.
What this interaction means in plain words
Atomoxetine and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atomoxetine belongs to Central Nervous System; Levofloxacin belongs to Anti Bacterial.
Why it happens
Additive effects on ventricular repolarization.
What to do
Check an ECG in patients with cardiac risk factors and correct electrolyte imbalances. Monitor for palpitations or syncope.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levofloxacin
- Dronedarone + Levofloxacin Contraindicated
- Ibutilide + Levofloxacin Contraindicated
- Levofloxacin + Thioridazine Contraindicated
- Levofloxacin + Vandetanib Contraindicated
- Levofloxacin + Ziprasidone Contraindicated
- Adagrasib + Levofloxacin Major
Other interactions of Atomoxetine
- Atomoxetine + Isocarboxazid Contraindicated
- Atomoxetine + Linezolid Contraindicated
- Atomoxetine + Phenelzine Contraindicated
- Atomoxetine + Procarbazine Contraindicated
- Atomoxetine + Rasagiline Contraindicated
- Atomoxetine + Selegiline Contraindicated
Frequently asked questions
Can I take Atomoxetine with Levofloxacin?
MediHelp rates the interaction as moderate. Atomoxetine and Levofloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have been linked to QTc prolongation, so use together may increase arrhythmia risk. The concern is greater with heart disease, bradycardia, or electrolyte abnormalities.
How serious is the interaction between Atomoxetine and Levofloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check an ECG in patients with cardiac risk factors and correct electrolyte imbalances. Monitor for palpitations or syncope.
What other medicines interact with Levofloxacin?
MediHelp also lists interactions of Levofloxacin with, for example, Dronedarone, Ibutilide, Thioridazine. The full list is on the Levofloxacin page.
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