Drug interactions
Atorvastatin + Dabigatran etexilate
Severity: Minor
Atorvastatin and Dabigatran etexilate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin is a weak P-glycoprotein inhibitor, but no clinically meaningful change in dabigatran exposure has been shown with its use. Routine coadministration is common and generally acceptable.
What this interaction means in plain words
Atorvastatin and Dabigatran etexilate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Dabigatran etexilate belongs to Cardiovascular.
Why it happens
Weak in vitro P-glycoprotein inhibition that is unlikely to substantially alter dabigatran absorption.
What to do
No dose adjustment is needed. Monitor for bleeding as for any patient on dabigatran.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dabigatran etexilate
- Dabigatran etexilate + Defibrotide Contraindicated
- Dabigatran etexilate + Ketorolac Contraindicated
- Dabigatran etexilate + Mifepristone Contraindicated
- Abciximab + Dabigatran etexilate Major
- Alteplase + Dabigatran etexilate Major
- Amiodarone + Dabigatran etexilate Major
Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Frequently asked questions
Can I take Atorvastatin with Dabigatran etexilate?
MediHelp rates the interaction as minor. Atorvastatin and Dabigatran etexilate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin is a weak P-glycoprotein inhibitor, but no clinically meaningful change in dabigatran exposure has been shown with its use. Routine coadministration is common and generally acceptable.
How serious is the interaction between Atorvastatin and Dabigatran etexilate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed. Monitor for bleeding as for any patient on dabigatran.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
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