Drug interactions
Atorvastatin + Deflazacort
Severity: Minor
Atorvastatin and Deflazacort: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin is a weak P-glycoprotein inhibitor and could theoretically raise deflazacort metabolite exposure. No clinically meaningful effect has been demonstrated.
What this interaction means in plain words
Atorvastatin and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Deflazacort belongs to Miscellaneous.
Why it happens
Possible weak P-glycoprotein inhibition by atorvastatin; clinical relevance is unproven.
What to do
No dose adjustment is required; monitor for usual corticosteroid adverse effects.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Other interactions of Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contraindicated
- Bcg vaccine live + Deflazacort Contraindicated
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Deflazacort + Measles mumps and rubella vaccine Contraindicated
- Deflazacort + Measles mumps and rubella vaccine live Contraindicated
- Deflazacort + Measles mumps rubella and varicella vaccine live Contraindicated
Frequently asked questions
Can I take Atorvastatin with Deflazacort?
MediHelp rates the interaction as minor. Atorvastatin and Deflazacort have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin is a weak P-glycoprotein inhibitor and could theoretically raise deflazacort metabolite exposure. No clinically meaningful effect has been demonstrated.
How serious is the interaction between Atorvastatin and Deflazacort?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is required; monitor for usual corticosteroid adverse effects.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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