Drug interactions
Atorvastatin + Erlotinib
Severity: Minor
Atorvastatin and Erlotinib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Atorvastatin may theoretically increase erlotinib exposure through weak P-glycoprotein inhibition. A clinically important effect has not been shown.
What this interaction means in plain words
Atorvastatin and Erlotinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Atorvastatin belongs to Cardiovascular; Erlotinib belongs to Oncology.
Why it happens
Possible weak P-glycoprotein inhibition by atorvastatin; clinical relevance is unproven.
What to do
No adjustment is needed; monitor for erlotinib rash and diarrhea as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Atorvastatin
- Atorvastatin + Tipranavir Contraindicated
- Atazanavir + Atorvastatin Major
- Atorvastatin + Clarithromycin Major
- Atorvastatin + Cobicistat Major
- Atorvastatin + Cyclosporin Major
- Atorvastatin + Danazol Major
Other interactions of Erlotinib
- Amobarbital + Erlotinib Major
- Apalutamide + Erlotinib Major
- Carbamazepine + Erlotinib Major
- Cobicistat + Erlotinib Major
- Darunavir + Erlotinib Major
- Dexlansoprazole + Erlotinib Major
Frequently asked questions
Can I take Atorvastatin with Erlotinib?
MediHelp rates the interaction as minor. Atorvastatin and Erlotinib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Atorvastatin may theoretically increase erlotinib exposure through weak P-glycoprotein inhibition. A clinically important effect has not been shown.
How serious is the interaction between Atorvastatin and Erlotinib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No adjustment is needed; monitor for erlotinib rash and diarrhea as usual.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
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