Drug interactions
Azathioprine + Influenza virus vaccine trivalent recombinant
Severity: Minor
Azathioprine and Influenza virus vaccine trivalent recombinant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Azathioprine may reduce antibody responses to the recombinant influenza vaccine. The vaccine is non-live and safe, so the concern is lower protection.
What this interaction means in plain words
Azathioprine and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Immunosuppression impairs lymphocyte proliferation and antibody production after vaccination.
What to do
Vaccinate annually as recommended; do not withhold because of azathioprine. Remain alert for influenza and treat promptly if it occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Azathioprine
- Adenovirus types 4 and 7 live + Azathioprine Contraindicated
- Azathioprine + Bcg vaccine live Contraindicated
- Azathioprine + Febuxostat Contraindicated
- Azathioprine + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Azathioprine + Measles mumps and rubella vaccine Contraindicated
- Azathioprine + Measles mumps and rubella vaccine live Contraindicated
Frequently asked questions
Can I take Azathioprine with Influenza virus vaccine trivalent recombinant?
MediHelp rates the interaction as minor. Azathioprine and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Azathioprine may reduce antibody responses to the recombinant influenza vaccine. The vaccine is non-live and safe, so the concern is lower protection.
How serious is the interaction between Azathioprine and Influenza virus vaccine trivalent recombinant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate annually as recommended; do not withhold because of azathioprine. Remain alert for influenza and treat promptly if it occurs.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
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